Xitrhon 200mg/5ml suspension 25ml

Trade name:

Xithrone

Compound:

Properties

A broad-spectrum antibacterial drug from the group of azalide macrolides, acts bacteriostatically. By binding to the 50S subunit of ribosomes, it inhibits the peptide translocase at the translation stage, inhibits protein synthesis, slows down the growth and reproduction of bacteria, and in high concentrations has a bactericidal effect. It acts on extra- and intracellularly located pathogens.

Microorganisms may be initially resistant to the action of an antibiotic or may acquire resistance to it.

Indications

Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:

— infections of the upper respiratory tract and ENT organs: pharyngitis, tonsillitis, sinusitis, otitis media;

— infections of the lower respiratory tract: acute bronchitis, exacerbation of chronic bronchitis, pneumonia, incl. caused by atypical pathogens;

Dosage and administration

For children from one year and older, the drug is prescribed at the rate of 10 mg / kg once a day for 3 days, or for 5 days, starting with a single dose of 10 mg / kg on day 1, then 5 mg / kg over the next 4 days. For children under 1 year of age, the drug is limited.

The prepared suspension is intended for oral administration, can be taken with meals. Immediately after taking the suspension, several sips of water or fruit juice should be drunk to flush out and swallow the remaining amount of the suspension in the mouth, as well as to eliminate the slightly bitter taste of the suspension.

Contraindications

— severe hepatic and/or renal insufficiency;

— children’s age up to 1 year;

-breast-feeding;

Side effects

From the digestive system: nausea, vomiting, diarrhea, abdominal pain, loose stools, flatulence, indigestion, anorexia, constipation, discoloration of the tongue, pseudomembranous colitis, cholestatic jaundice, hepatitis, changes in laboratory parameters of liver function, liver failure, liver necrosis (possibly fatal).

Allergic reactions: itching, skin rashes, angioedema, urticaria, photosensitivity, anaphylactic reaction (in rare cases fatal), erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.

From the side of the cardiovascular system: palpitations, arrhythmia, ventricular tachycardia, an increase in the QT interval, bidirectional ventricular tachycardia.