
Nevilob 2.5 mg 14 tablets
Tradename
Nevilob
Nevilob
Composition
Each tablet contains:
Nebivolol (as hydrochloride) 2.5 mg
Auxiliary components:
Lactose monohydrate, starch, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, polysorbate.
Properties
Cardioselective beta1-blocker. Nebivolol has hypotensive, antianginal and antiarrhythmic effects. Reduces high blood pressure at rest, during physical exertion and stress. Competitively and selectively blocks postsynaptic β1-adrenergic receptors, making them inaccessible to catecholamines, modulates the release of endothelial vasodilating factor nitric oxide (NO).
Indications
-arterial hypertension;
-IHD: prevention of angina attacks;
— chronic heart failure (as part of combination therapy).
Contraindications
— acute heart failure;
— chronic heart failure in the stage of decompensation;
— severe arterial hypotension;
Side effects
From the nervous system: often — headache, dizziness, fatigue, weakness, paresthesia;
From the gastrointestinal tract: often — dryness of the oral mucosa, nausea, constipation, diarrhea;
From the respiratory system: often — shortness of breath; infrequently — bronchospasm, rhinitis.