Zefikam 8 mg 20 tablets

Tradename

Zefikam

Composition

Each tablet contains:

Lornoxicam 8 mg

Properties

NSAIDs, belongs to the class of oxicams. It has a pronounced anti-inflammatory and analgesic effect, and also has an antipyretic and antiplatelet effect.

The mechanism of action is associated with the suppression of inflammatory factors; inhibition of prostaglandin synthesis due to inhibition of COX1 and COX2, which leads to disruption of the metabolism of arachidonic acid and inhibition of prostaglandin synthesis both in the focus of inflammation and in healthy tissues. Suppresses the exudative and proliferative phases of inflammation.

Indications

Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, articular syndrome with exacerbation of gout, bursitis, tendovaginitis.

Moderate and severe pain syndrome (including arthralgia, myalgia, neuralgia, lumbago, sciatica, migraine, toothache and headache, algomenorrhea, pain in trauma, burns. Febrile syndrome (with colds and infectious diseases).

Method of administration and dosage:

Contraindications

Acute bleeding from the gastrointestinal tract, gastric ulcer and duodenal ulcer in the acute phase, ulcerative colitis in the acute phase, bronchial asthma, severe chronic heart failure, hypovolemia, blood clotting disorders (including hemophilia, hemorrhagic diathesis, thrombocytopenia), severe hepatic and / or renal failure, deficiency of glucose-6-phosphate dehydrogenase, cerebral hemorrhage (including suspicion), pregnancy, lactation, children and adolescents under 18 years of age, hypersensitivity to lornoxicam, acetylsalicylic acid or other NSAIDs.

Precautionary measures:

Use with caution in case of erosive and ulcerative lesions and bleeding from the gastrointestinal tract (in history), moderate renal failure, conditions after surgery, in elderly patients (over 65 years old), in patients weighing less than 50 kg.

Side effects

From the digestive system: abdominal pain, diarrhea, dyspepsia, nausea, vomiting, heartburn, diarrhea; rarely — flatulence, dry mouth, gastritis, esophagitis, erosive and ulcerative lesions of the mucous membrane of the stomach and intestines, bleeding from the gastrointestinal tract (including rectal), liver dysfunction.

From the side of the central nervous system: rarely — dizziness, headache, drowsiness, a state of agitation, sleep disturbances, depression, tremor, aseptic meningitis.

From the hematopoietic system: rarely — leukopenia, thrombocytopenia, agranulocytosis.