Zurcal 20 mg 14 tablets

Tradename

Zurcal

Composition

Each tablet contains:

Pantoprazole 20 mg

Auxiliary components:

Sodium carbonate, Mannitol (E421) Crospovidone Povidone K90 Calcium stearate

Properties

Pantoprazole is a substituted benzimidazole that inhibits the secretion of hydrochloric acid in the stomach by specifically blocking the proton pump of parietal cells. Pantoprazole is converted to its active form, cyclic sulfenamide, in an acidic environment in parietal cells, where it inhibits the enzyme H +, K + -ATPase, i.e. the final stage of the formation of hydrochloric acid in the stomach.

Indications

gastroesophageal reflux disease, reflux esophagitis;

eradication of Helicobacter pylori (as part of complex therapy);

duodenal ulcer; stomach ulcer;

Contraindications

Hypersensitivity to pantoprazole, benzimidazole derivatives or other components of the drug. Simultaneous reception of atazanavir. Due to insufficient data, the use of pantoprazole for the treatment of children under 12 years of age is not recommended.

Precautionary measures:

In the presence of any alarming symptom (for example, significant weight loss, repeated vomiting, dysphagia, vomiting of blood, anemia, melena) and if a stomach ulcer is present or suspected, malignant neoplasm should be ruled out, since pantoprazole treatment can relieve symptoms and delay diagnosis.

Side effects

In about 5% of patients, side effects of the drug may occur.

The most common side effects: diarrhea and headache — occur in about 1% of patients.

From the nervous system and sensory organs: infrequently — headache, dizziness, sleep disturbance. Rarely, visual acuity, depression (and aggravation). Very rarely — disorientation, paresthesia. The frequency is unknown — hallucinations, confusion (especially in predisposed patients, as well as exacerbation of these symptoms if they were present earlier).