Optipred 10mg / ml drops 5 ml

Tradename

Optipred

Composition

Each ml contains:

Prednisolone acetate 10 mg

Auxiliary components:

Benzalkonium chloride, polysorbitol, sodium citrate, sodium chloride, edetate disodium, water for injection.

Properties

GCS, a dehydrated analogue of hydrocortisone, has a pronounced antiinflammatory, antiallergic and antiexudative effect. By interacting with a specific protein receptor in target tissues, it regulates the expression of corticoid-dependent genes and thus affects on protein synthesis. Reduces the formation, release and activity of inflammatory mediators (histamine, kinin, Pg, lysosomal enzymes). Suppresses cell migration to the site of inflammation; reduces vasodilation and increased vascular permeability in the focus of inflammation. Stabilizes lysosomal enzyme leukocyte membranes; inhibits the synthesi antibodies and disrupts antigen recognition.

Inhibits the release of interleukinl, interleukin2, interferon gamma from lymphocytes and macrophages. Induces the formation of lipocortin, inhibits the release of inflammatory mediators by eosinophils and stabilizes mast cell membranes. All of these effects are involved in suppressing the inflammatory response in tissues in response to mechanical, chemical, or immune damage.

Indications

Non-infectious inflammatory diseases of the anterior segment of the eye — iritis, iridocyclitis, uveitis, episcleritis, scleritis, conjunctivitis, parenchymal and disc-shaped keratitis without damage to the corneal epithelium, allergic conjunctivitis, blepharoconjunctivitis, sympathetic processes of post-ocular blepharitis and surgical blepharitis, eye inflammation and surgery

Method of administration and dosage:

The solution is instilled into the conjunctival sac, 1-2 drops 3 times a day. In acute cases, the drug is instilled every 2-4 hours. After eye operations, it is prescribed only 3-5 days a the operation.

Contraindications

Hypersensitivity, viral and fungal diseases of the eyes, acute purulent conjunctivitis, purulent infection of the mucous membrane of the eye and eyelids, purulent corneal ulcer, viral conjunctivitis, trachoma, glaucoma, damage to the integrity of the corneal epithelium; tuberculosis of the eyes; condition after removal of the corneal foreign body.

Precautions:

During treatment, it is necessary to monitor intraocular pressure and the condition of the cornea.

Side effects

With prolonged use:

— increased intraocular pressure, damage to the optic nerve, subcapsular cataract, impaired visual acuity and narrowing of the visual field (blurred or loss of vision, eye pain, nausea, dizziness), with thinning of the cornea

-the danger of perforation;