
Primperan 10mg / 2ml 12 ampoules
Tradename
Primperan
Primperan
Composition
Each ampoule contains:
Metoclopramide hydrochloride 10.00 mg
Auxiliary components:
Sodium chloride, water for injection.
Properties
Antiemetic. A specific blocker of dopamine (D2) and serotonin (5-NTZ) receptors, inhibits the chemoreceptors of the trigger zone of the brain stem, weakens the sensitivity of the visceral nerves that transmit impulses from the pylorus of the stomach and duodenum to the vomiting center.
Indications
— vomiting, nausea, hiccups of various origins (in some cases, it can be effective in vomiting caused by radiation therapy or taking cytostatics);
— atony and hypotension of the stomach and intestines (in particular, postoperative);
-dyskinesia of the biliary tract in the hypomotor type;
Contraindications
— bleeding from the gastrointestinal tract;
— stenosis of the pylorus of the stomach;
-mechanical intestinal obstruction;
Side effects
From the nervous system: extrapyramidal disorders — spasm of the facial muscles, trismus, rhythmic protrusion of the tongue, bulbar type of speech.
From the digestive system: constipation or diarrhea, rarely — dry mouth.
From the side of the cardiovascular system: atrioventricular block.