Tiratam 100mg / ml suspension 120 ml

Tradename

Tiratam

Tiratam

Composition

Each 1 ml of solution contains:

Levetiracetam 100 mg.

Auxiliary components:

Sucrose, sodium methylparaben, sodium propylparaben, sorbitol 70%, sodium carboxymethylcellulose, glycerol, banana flavor, aspartame, purified water.

Properties

Antiepileptic agent, pyrrolidone derivative (S-enantiomer of α-ethyl-2-oxo-1-pyrrolidine-acetamide). The chemical structure differs from the known antiepileptic drugs. One of the mechanisms is based on the proven binding to the SV2A synaptic vesicle glycoprotein contained in the gray matter of the brain and spinal cord. It is believed that in this way the anticonvulsant effect is realized, which is expressed in counteracting the hypersynchronization of neural activity. Does not alter normal neurotransmission, but suppresses epileptiform neuronal outbursts induced by the GABA agonist bikuculin and the excitation of glutamate receptors. The activity of levetiracetam has been confirmed in relation to both focal and generalized epileptic seizures (epileptiform manifestations / photoparoxysmal reaction).

Indications

As monotherapy for the treatment of partial seizures with or without secondary generalization in patients over 16 years of age with a newly diagnosed epilepsy.

As part of additional therapy during treatment: partial convulsions with or without secondary generalization in patients older than 1 month (in the appropriate dosage form for this age) with epilepsy; myoclonic seizures in patients over 12 years old with juvenile myoclonic epilepsy; primary generalized tonic-clonic seizures in patients from 12 years of age with idiopathic generalized epilepsy.

Method of administration and dosage:

Contraindications

Hypersensitivity to levetiracetam or other pyrrolidone derivatives, children under 1 month of age.

Carefully:

Elderly patients (over 65 years old); liver disease in the stage of decompensation; renal failure.

Side effects

From the hematopoietic system: infrequently — thrombocytopenia, leukopenia; rarely — neutropenia, pancytopemia.

From the side of metabolism: often — anorexia; infrequently — increase / decrease in body weight.

From the side of the central nervous system: very often — drowsiness, headache; often — mood swings, emotional lability, depression, aggressiveness, insomnia, nervousness.