Epicotil 20 mg 3 ampoules

Tradename

Epicotil

Epicotil

Composition

Each bottle of powder contains:

Tenoxicam 20 mg

Each solvent ampoule contains:

Water for injection 2 ml

Properties

NSAIDs of the oxicam class. It has a powerful analgesic and anti-inflammatory effect, the antipyretic effect is less pronounced. The mechanism of action is based on the inhibition of the activity of isoenzymes COX-1 and COX-2, as a result of which the synthesis of prostaglandins in the focus of inflammation, as well as in other tissues of the body, decreases. In addition, tenoxicam reduces the accumulation of leukocytes at the site of inflammation. A distinctive feature of tenoxicam is its long duration of action. His T1 / 2 is 72 hours.

Indications

Symptomatic treatment as an anti-inflammatory and analgesic agent: rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, articular syndrome with exacerbation of gout, bursitis, tendovaginitis; pain syndrome of weak and moderate intensity (arthralgia, myalgia, neuralgia, migraine, toothache and headache, algomenorrhea); pain with injuries, burns. Inflammatory and degenerative diseases of the musculoskeletal system, accompanied by pain, such as sciatica, lumbago, epicondylitis.

Method of administration and dosage:

Applied intravenously, intramuscularly, the dose is 20 mg 1 time / day. The duration of the course of treatment is 7-14 days.

Contraindications

Hypersensitivity to tenoxicam and other NSAIDs; erosive and ulcerative lesions of the gastrointestinal tract (including in history), gastrointestinal bleeding (including in history), inflammatory diseases of the gastrointestinal tract (Crohn’s disease or ulcerative colitis in the acute phase), severe renal failure (CC less than 30 ml / min), progressive kidney disease, severe liver failure; complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs (including history); established diagnosis of diseases of the blood coagulation system, decompensated heart failure, therapy of perioperative pain during coronary artery bypass grafting. Pregnancy, lactation (breastfeeding); children and adolescents up to 16 years old.

Precautionary measures:

When using tenoxicam, you should carefully monitor the function of the gastrointestinal tract. If the first signs of ulcerogenesis or gastrointestinal bleeding are detected, tenoxicam should be immediately canceled.

Side effects

From the hematopoietic system: often — agranulocytosis, leukopenia.

From the nervous system: often — dizziness, headache, drowsiness, depression, agitation, hearing loss, tinnitus, irritation and swelling of the eyelids, blurred vision.

From the digestive system: very often — dyspepsia (nausea, vomiting, heartburn, diarrhea, flatulence), NSAID gastropathy, abdominal pain, stomatitis, anorexia, liver dysfunction.