
Unictam 375mg 1 bottle for preparation of solution for injection
Trade name:
Uniktam
Unictam
Composition
Each bottle contains:
Sodium sulbactam 125 mg
Sodium ampicillin 250 mg
Each ampoule contains:
Water for injection 5 ml.
Properties
Combined broad-spectrum antibacterial agent.
Ampicillin is an antibiotic from the group of semisynthetic penicillins, the bactericidal effect of which is associated with inhibition of the synthesis of proteins in the cell wall of microorganisms.
Sulbactam — an irreversible inhibitor of beta-lactamases; expands the spectrum of activity of ampicillin against resistant strains, the resistance of which develops under the influence of beta-lactamases; does not change the activity of ampicillin against susceptible strains; binding to some penicillin-binding proteins of bacteria, it exhibits synergism when used simultaneously with beta-lactam antibiotics. Stable in aqueous solution, has independent antibacterial activity against the family Neisseriaceae and Acinetobacter spp., Resistant to the action of most plasmid beta-lactamases.
Indications
Treatment of infectious and inflammatory diseases caused by sensitive pathogens: respiratory infections (including pneumonia, lung abscess, chronic bronchitis, pleural empyema); ENT infections (including sinusitis, tonsillitis, otitis media); infections of the urinary tract and genital organs (pyelonephritis, pyelitis, cystitis, urethritis, prostatitis, endometritis); biliary tract infections (cholecystitis, cholangitis); infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatitis); gastrointestinal infections (dysentery, salmonellosis, salmonella carriers); infections of bones and joints; septic endocarditis; meningitis; sepsis; peritonitis; scarlet fever; gonococcal infection.
Prevention of postoperative complications during operations on the abdominal and pelvic organs.
Method of administration and dosage:
Contraindications
Hypersensitivity to the components of the drug; Infectious mononucleosis; lactation period (breastfeeding).
With caution:
Hepatic and / or renal failure, pregnancy.
Side effects
From the digestive system: nausea, vomiting, decreased appetite, diarrhea, increased activity of «hepatic» transaminases;
From the side of hematopoiesis and hemostasis system: anemia, leukopenia, thrombocytopenia.
From the nervous system: drowsiness, malaise, headache.