Statukast 4 mg granules 10 sachets

Tradename

Statucast

Statukast

Composition

Each sachet contains:

Montelukast sodium 4 mg

Auxiliary components:

Mannitol, magnesium stearate, hydroxypropyl cellulose.

Properties

Leukotriene receptor antagonist. Montelukast binds with high selectivity and chemical affinity to CysLT1 receptors (instead of other pharmacologically important airway receptors such as prostaglandin, cholinergic or β-adrenergic receptors).

Montelukast inhibits the physiological effect of cisgenyl leukotrienes LTC4, LTD4 and LTE4 by binding to CysLT1 receptors without stimulating these receptors. Montelukast inhibits CysLT1 receptors of the airway epithelium, thereby simultaneously having the ability to inhibit bronchospasm caused by inhalation of LTD4 in patients with bronchial asthma.

Indications

Prevention and long-term treatment of bronchial asthma, including: prevention of day and night symptoms of the disease; treatment of bronchial asthma in patients with hypersensitivity to acetylsalicylic acid; prevention of exercise-induced bronchospasm.

Relief of day and night symptoms of seasonal allergic rhinitis.

Method of administration and dosage:

Contraindications

— hypersensitivity to any component of the drug;

-phenylketonuria.

Precautionary measures:

Side effects

The statucast is generally well tolerated. The following possible side effects are mild and usually do not require discontinuation of therapy:

— hypersensitivity reactions (anaphylaxis, Quincke’s edema, urticaria, rash, itching), and very rarely — eosinophilic liver infiltration;

— sleep disturbances, hallucinations, flutter, drowsiness, irritability, fatigue, insomnia, excessive sweating, headache;