Trental SR 400 mg 20 tablets

Tradename

Trental SR

Trental SR

Composition

Each tablet contains:

Pentoxifylline 400 mg

Auxiliary components:

Hydroxyethyl cellulose, talc, magnesium stearate, sucrose, titanium dioxide, propylene glycol.

Properties

Vasodilator. Pentoxifylline improves microcirculation and blood rheological properties. The mechanism of action of pentoxifylline is associated with inhibition of phosphodiesterase and the accumulation of cyclic AMP in the cells of vascular smooth muscle and blood cells. Pentoxifylline inhibits the aggregation of platelets and erythrocytes, increases their elasticity, reduces the level of fibrinogen in plasma and enhances fibrinolysis, which reduces blood viscosity and improves its rheological properties.

It has a weak myotropic vasodilator effect. Pentoxifylline slightly reduces the total peripheral resistance and slightly dilates the coronary vessels.

In general, Trental improves microcirculation and oxygen supply to tissues in the central nervous system and in the extremities, to a lesser extent in the kidneys.

Indications

— Peripheral circulation disorders caused by atherosclerosis, diabetes mellitus (diabetic angiopathy), inflammation;

— acute and chronic ischemic cerebral circulation disorders;

— atherosclerotic and discirculatory encephalopathy;

Contraindications

— acute myocardial infarction;

— massive bleeding;

— acute hemorrhagic stroke;

Side effects

Most often, when taking Trental, adverse events from the gastrointestinal tract may appear (nausea, a feeling of fullness in the abdomen, stomach cramps, vomiting, diarrhea). Dizziness and headache may sometimes occur. Occasionally, you can observe a decrease in blood pressure, angina pectoris, an abnormal heart rhythm, a feeling of flushing.

Storage method:

Store at a temperature not exceeding 25 degrees. In a place protected from light.