Vardo 20 mg 4 tablets

Trade name:

Varde

Composition

Each tablet contains:

Vardenafil 20 mg

Auxiliary components:

Microcrystalline cellulose, magnesium stearate, crospovidone.

Properties

A drug for the treatment of erectile dysfunction, PDE5 inhibitor.

Penile erection is a hemodynamic process, which is based on the relaxation of the smooth muscles of the cavernous bodies and the arterioles located in it. During sexual stimulation, nitric oxide (NO) is released from the nerve endings of the corpus cavernosum, which activates the enzyme guanylate cyclase, which leads to an increase in the content of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. As a result, the smooth muscles of the cavernous bodies are relaxed, which contributes to an increase in blood flow to the penis.

Vardenafil blocks PDE5, under the influence of which the breakdown of cGMP occurs, as a result of which the action of endogenous NO in the corpus cavernosum during sexual stimulation is enhanced, which determines the ability of vardenafil to enhance the natural response to sexual stimulation.

Indications

Erectile dysfunction (the inability to achieve and maintain an erection necessary for intercourse).

Method of administration and dosage:

At the beginning of treatment, the recommended dose is 10 mg. It is taken orally, if necessary, approximately 25-60 minutes before sexual intercourse. Along with this, vardenafil can also be taken at any time in the period from 4-5 hours to 25 minutes before sexual activity. The maximum recommended frequency of admission is 1 time / day.

Contraindications

Simultaneous therapy with nitrates or drugs that are donors of nitric oxide; children and adolescents up to 18 years old; hypersensitivity to vardenafil.

Precautionary measures:

Use with caution in patients with anatomical deformity of the penis (curvature, cavernous fibrosis or Peyronie’s disease), as well as in patients with diseases that predispose to the development of priapism (sickle cell anemia, multiple myeloma or leukemia).

Side effects

From the nervous system: possible headache, dizziness; rarely — increased muscle tone.

From the side of the cardiovascular system: redness of the face is possible; rarely — an increase in blood pressure, a decrease in blood pressure.

From the digestive system: possible — dyspepsia, nausea.