Cetafen 30 tablets

Tradename

Cetafen (Cetafen)

Compound:

Each tablet contains:

Ibuprofen 200 mg

Paracetamol 325 mg

Auxiliary components:

Starch, microcrystalline cellulose, aerosil.

Properties

Combined drug, the action of which is due to its constituent components.

Ibuprofen — NSAIDs, has analgesic, anti-inflammatory, antipyretic effect. By inhibiting COX-1 and COX-2, it disrupts the metabolism of arachidonic acid, reduces the amount of prostaglandins (mediators of pain, inflammation and hyperthermia), both in the focus of inflammation and in healthy tissues, and suppresses the exudative and proliferative phases of inflammation.

Paracetamol — indiscriminately blocks COX, mainly in the central nervous system, has little effect on water-salt metabolism and the gastrointestinal mucosa. It has an analgesic and antipyretic effect. In inflamed tissues, peroxidases neutralize the effect of paracetamol on COX-1 and COX-2, which explains the low anti-inflammatory effect.

Indications

The drug is intended for symptomatic therapy, reducing pain and inflammation at the time of use, does not affect the progression of the disease.

Dosage and administration

The drug is taken orally (before or 2-3 hours after a meal), without chewing, drinking plenty of water.

Adults — 1 tab. 3 times / day. The maximum daily dose is 3 tab.

Children over 12 years old (body weight over 40 kg) — 1 tab. 2 times/day

Contraindications

— peptic ulcer of the stomach and duodenum in the acute phase;

— gastrointestinal bleeding;

— severe renal failure (CC less than 30 ml / min);

Side effects

From the digestive system: NSAID-gastropathy — nausea, vomiting, heartburn, anorexia, epigastric discomfort or pain, diarrhea, flatulence.

From the nervous system and sensory organs: headache, dizziness, insomnia, anxiety, nervousness.

From the side of the cardiovascular system: heart failure, increased blood pressure, tachycardia.