Concor Amlo 5/5 mg 30 tablets

Tradename

Concor Amlo

Composition

Each tablet contains:

bisoprolol fumarate 5 mg

amlodipine besylate 5 mg

Auxiliary components:

microcrystalline cellulose, sodium carboxymethyl starch (type A), magnesium stearate, colloidal anhydrous silicon dioxide.

Properties

Amlodipine blocks calcium channels, reduces the transmembrane transition of calcium ions into the cell (to a greater extent in vascular smooth muscle cells than in cardiomyocytes).

The antihypertensive effect of amlodipine is due to a direct relaxing effect on vascular smooth muscle cells, which leads to a decrease in peripheral vascular resistance.

Bisoprolol is a selective beta1-blocker, without its own sympathomimetic activity, does not have a membrane stabilizing effect.

Indications

Arterial hypertension: replacement of therapy with monocomponent drugs amlodipine and bisoprolol in the same doses.

Method of administration and dosage:

Oral tablets. The tablets should be taken in the morning, regardless of food intake, without chewing. The risk is only intended to facilitate breaking for ease of swallowing. Not to be divided into equal doses!

Contraindications

— hypersensitivity to amlodipine, other dihydropyridine derivatives, bisoprolol and / or any of the excipients;

— children under 18 years of age (efficacy and safety have not been established).

Precautionary measures:

Side effects

Amlodipine:

From the nervous system: often — drowsiness, dizziness, headache (especially at the beginning of treatment).

From the side of the organ of vision: often — visual impairment (including diplopia).