Livagol 450 mg 20 capsules

Tradename

Livagoal

Composition

Each capsule contains:

Ursodeoxycholic acid 450 mg

Auxiliary components:

Povidone, dicalcium phosphate, methylparaben, propylparaben, aerosil, magnesium stearate.

Properties

Hepatoprotector. Ursodeoxycholic acid is a bile acid. Reduces cholesterol in bile mainly by dispersing cholesterol and forming a liquid crystal phase. It affects the enterohepatic circulation of bile salts, reducing the reabsorption of endogenous, more hydrophobic and potentially toxic compounds in the intestine.

In vitro studies have shown that ursodeoxycholic acid has a direct hepatoprotective effect and reduces the hepatotoxicity of hydrophobic bile salts.

It has an effect on immunological reactions, reducing the pathological expression of class I HLA antigens on hepatocytes and suppressing the production of cytokines and interleukins.

Indications

— dissolution of small and medium cholesterol stones with a functioning gallbladder;

— prevention of recurrence of stone formation after cholecystectomy;

-biliary reflux gastritis and reflux esophagitis;

Contraindications

-increased sensitivity to the components of the drug;

X-ray positive (high calcium) gallstones;

— not functioning gallbladder;

Side effects

Gastrointestinal disorders: often — loose stools or diarrhea; very rarely — acute pain in the right upper abdomen (in the treatment of primary biliary cirrhosis).

Disorders from the liver and biliary tract: very rarely — calcification of gallstones, decompensation of liver cirrhosis, which disappears after discontinuation of the drug (in the treatment of advanced stages of primary biliary cirrhosis).

Skin and subcutaneous tissue disorders: very rarely — urticaria.