Garopride 50 mg 30 tablets

Tradename

Garopride

Compound:

Each tablet contains:

Itoprid hydrochloride 50 mg

Properties

Itopride hydrochloride is a gastroprokinetic drug for oral administration. The dosage form and composition of the tablets provide an immediate release of the active substance. Itopride is characterized by a dual mechanism of action: antagonism to D2-dopamine receptors and inhibition of acetylcholinesterase. As a result of the action of itopride, the concentration of acetylcholine increases, which leads to increased gastric motility, increased tone of the lower esophageal sphincter (LES), accelerated gastric emptying and improved gastroduodenal coordination.

Itopride hydrochloride also has an antiemetic effect by interacting with D2-dopamine receptors located in the chemoreceptor trigger zone of the medulla oblongata. Itopride causes dose-dependent suppression of apomorphine-induced vomiting.

Indications

Treating gastrointestinal symptoms associated with impaired gastric motility or delayed gastric emptying, such as:

bloating;

-fast saturation;

Contraindications

— gastrointestinal bleeding, mechanical obstruction or perforation of the gastrointestinal tract;

-pregnancy;

-period of lactation (breastfeeding);

Side effects

From the gastrointestinal tract: often — abdominal pain, diarrhea; infrequently — increased salivation.

Laboratory and instrumental data: infrequently — an increase in ALT activity, a decrease in the number of leukocytes.

From the nervous system: infrequently — dizziness, headache.