Roaccutane 20 mg 30 capsules

Tradename

Roaccutane

Compound:

Each capsule contains:

Isotretinoin 20 mg

Auxiliary components:

Soybean oil, yellow beeswax, hydrogenated soybean oil, partially hydrogenated soybean oil.

Properties

Retinoid for systemic treatment of acne.

Isotretinoin is a stereoisomer of all-trans retinoic acid (tretinoin).

The exact mechanism of action of Roaccutane has not yet been elucidated, however, it has been established that the improvement in the clinical picture of severe forms of acne is associated with the suppression of the activity of the sebaceous glands and a histologically confirmed decrease in their size. In addition, the anti-inflammatory effect of isotretinoin on the skin has been proven.

Indications

— severe forms of acne (nodular cystic, conglobate acne or acne with a risk of scarring);

— acne, not amenable to other types of therapy.

Dosage and administration

Inside, during meals once or twice a day.

The therapeutic efficacy of Roaccutane and its side effects are dose dependent and vary from patient to patient. This dictates the need for individual dose selection during treatment.

Treatment with Roaccutane should begin with a dose of 0.5 mg/kg body weight/day. In most patients, the dose ranges from 0.5 to 1.0 mg / kg of body weight per day. Patients with very severe forms of the disease or with acne of the trunk may require higher daily doses — up to 2.0 mg / kg / day.

Contraindications

-liver failure;

— hypervitaminosis A;

— severe hyperlipidemia;

Side effects

Symptoms of vitamin A hypervitaminosis: dry skin, mucous membranes.

On the part of the skin and its appendages: very often — cheilitis, dermatitis, dry skin, localized peeling, itching, erythematous rash, increased.

At the beginning of treatment, an exacerbation of acne is possible, which persists for several weeks.