Triplixam 10mg/2.5mg/10mg 15 tablets

Tradename

Triplixam 10mg/2.5mg/10mg (Triplixam 10mg/2.5mg/10mg)

Compound:

Each tablet contains:

perindopril arginine 10 mg

indapamide 2.5 mg

amlodipine besylate 13.870 mg, which corresponds to the content of amlodipine 10 mg

Auxiliary components:

calcium carbonate + pregelatinized corn starch, microcrystalline cellulose, sodium croscarmellose, magnesium stearate, colloidal silicon dioxide, pregelatinized starch.

Film shell: glycerol, hypromellose, macrogol-6000, magnesium stearate, titanium dioxide.

Properties

Triplixam is a combination drug that includes three antihypertensive components, each of which complements the action of others in controlling blood pressure in patients with arterial hypertension. Amlodipine is a slow calcium channel blocker (BMCC), a dihydropyridine derivative, indapamide is a sulfonamide diuretic, perindopril is an inhibitor of the enzyme that converts angiotensin I to angiotensin II (ACE inhibitor).

The pharmacological properties of Triplixam combine the properties of each of its active ingredients. In addition, the combination of amlodipine, indapamide and perindopril enhances the antihypertensive effect of each of the components.

Indications

Therapy of arterial hypertension with a decrease in blood pressure while taking amlodipine, indapamide and perindopril in the same doses.

Dosage and administration

The drug is taken orally, 1 tab. 1 time / day, preferably in the morning before meals.

The dose of Triplixam is selected after the previous dose titration of the individual components. The maximum daily dose is 1 tab. at a dosage of 10 mg + 2.5 mg + 10 mg.

Contraindications

— hypersensitivity to the active and auxiliary substances that are part of the drug, sulfonamide derivatives, dihydropyridine derivatives, other ACE inhibitors, any other substances that are part of the drug;

— patients on hemodialysis;

— untreated heart failure in the stage of decompensation;

Side effects

The most common adverse reactions reported with perindopril, indapamide and amlodipine are dizziness, headache, paresthesia, drowsiness, dysgeusia, blurred vision, diplopia, tinnitus, vertigo, palpitation, flushing, hypotension (and related symptoms). ), cough, shortness of breath, gastrointestinal disturbances (abdominal pain, constipation, diarrhea, dyspepsia, nausea, vomiting, change in the rhythm of bowel movements), pruritus, skin rashes, maculopapular rash, muscle cramps, swelling of the ankles, asthenia, edema and fatigue.

Storage method:

Store at a temperature not exceeding 30 degrees.