
Fam 10 mg 20 tablets
Tradename
Fam (Fam)
Compound:
Each tablet contains:
Ketorolac tromethamine 10 mg
Auxiliary components:
Starch, magnesium stearate, talc, aerosil.
Properties
Ketorolac — NSAIDs, has a pronounced analgesic (pain-relieving) effect, also has an anti-inflammatory and moderate antipyretic effect.
The mechanism of action is associated with non-selective inhibition of the activity of COX-1 and COX-2 enzymes, mainly in peripheral tissues, resulting in inhibition of the biosynthesis of prostaglandins — modulators of pain sensitivity, inflammation and thermoregulation. Ketorolac is a racemic mixture of R(+) and S(-)-enantiomers, while the analgesic (pain-relieving) effect is due to the S(-)-enantiomer.
Ketorolac does not affect opioid receptors, does not depress breathing, does not cause drug dependence, does not have a sedative and anxiolytic effect.
Indications
— pain syndrome of strong and moderate severity: injuries, toothache, pain in the postoperative period, cancer, myalgia, arthralgia, neuralgia, sciatica, dislocations, sprains, rheumatic diseases.
It is intended for symptomatic therapy, reducing pain and inflammation at the time of use, does not affect the progression of the disease.
Dosage and administration
The drug should be used orally once or repeatedly, depending on the severity of the pain syndrome.
A single dose is 10 mg, with repeated administration it is recommended to take 10 mg up to 4 times / day, depending on the severity of pain. The maximum daily dose should not exceed 40 mg.
When taken orally, the duration of the course should not exceed 5 days.
Contraindications
— complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs (including history);
— urticaria, rhinitis caused by taking NSAIDs (in history);
— intolerance to drugs of the pyrazolone series;
Side effects
From the digestive system: often (especially in elderly patients over 65 years of age with a history of erosive and ulcerative lesions of the gastrointestinal tract) — gastralgia, diarrhea.
From the side of the central nervous system and peripheral nervous system: often — headache, dizziness, drowsiness.
Other: often — edema (including face, shins, ankles, fingers, feet), weight gain; less often — excessive sweating; rarely — swelling of the tongue, fever.