Maxofage XR 1000 mg 30 tablets

Trade name:

Maxophage XR

Maxophage XR

Properties

Metformin is a biguanide with a hypoglycemic effect that reduces both basal and postprandial glucose levels in blood plasma. Does not stimulate insulin secretion and therefore does not cause hypoglycemia. Increases the sensitivity of peripheral receptors to insulin and the utilization of glucose by cells. Reduces hepatic glucose production by inhibiting gluconeogenesis and glycogenolysis. Delays the absorption of glucose in the intestine.

Metformin stimulates glycogen synthesis by acting on glycogen synthase. Increases the transport capacity of all types of membrane glucose carriers.

While taking metformin, the patient’s body weight either remains stable or moderately decreases.

Indications

Type 2 diabetes mellitus, especially in obese patients with diet and exercise failure in adults as monotherapy or in combination with other oral hypoglycemic drugs, or with insulin.

Dosage and administration

Take inside.

The tablets are swallowed whole, without chewing, with a sufficient amount of liquid, 1 time per day during or after dinner.

The dose of Glucophage XR 1000 mg is selected by the doctor individually for each patient based on the results of measuring the concentration of glucose in the blood.

Contraindications

— hypersensitivity to metformin or to any excipient;

-diabetic ketoacidosis, diabetic precoma, coma;

— renal failure or impaired renal function (CC less than 45 ml / min);

Side effects

Gastrointestinal disorders:

Very often — nausea, vomiting, diarrhea, abdominal pain, lack of appetite. Most often they occur in the initial period of treatment and in most cases resolve spontaneously.

Skin and subcutaneous tissue disorders: