Cardura 1mg

Trade Name:

Cardura

Composition

Each tablet contains:

Doxazosin mesylate 1.213 mg,

which corresponds to the content of Doxazosin 1 mg

Inactive ingredients:

Sodium carboxymethyl starch, lactose monohydrate, microcrystalline cellulose, magnesium stearate, sodium lauryl sulfate.

Properties

The appointment of doxazosin to patients with symptoms of benign prostatic hyperplasia (BPH) leads to a significant improvement in urodynamics and a decrease in the manifestations of symptoms of the disease. This action of the drug is associated with a selective blockade of α1-adrenergic receptors located in the stroma and capsule of the prostate and bladder neck.

It has been proven that doxazosin is a blocker of α1-adrenergic receptors subtype 1A, which make up approximately 70% of all α1-adrenergic receptor subtypes located in the prostate gland. This explains its effect in patients with BPH.

The maintenance effect of doxazosin treatment and its safety have been proven with long-term use of the drug (for example, up to 48 months).

Indications

— benign of prostatic hyperplasia;

— for the treatment of urinary retention and other symptoms associated with BPH;

— arterial hypertension (as part of combination therapy).

Dosage and administration

The drug is taken orally, in the morning or in the evening.

Benign prostatic hyperplasia:

The recommended initial dose of Cardura is 1 mg 1 time / day in order to minimize the possibility of developing postural hypotension and / or syncope. The dose can be increased to 2 mg, and then up to 4 mg and up to the maximum recommended dose of 8 mg. The recommended interval for increasing the dose is 1-2 weeks. Usually the recommended dose is 2-4 mg 1 time / day.

Contraindications

— severe liver failure (due to lack of experience in this category of patients);

-urinary tract infections;

-anuria;

Side effects

On the part of the organ of vision: often — a violation of color perception; infrequently — atonic iris syndrome.

From the digestive system: often — abdominal pain, diarrhea, dyspepsia, dryness of the oral mucosa; infrequently — flatulence, constipation, vomiting.

From the nervous system: often — paresthesia; infrequently — hypesthesia, tremor.

Storage

Store at a temperature not exceeding 30°C.

Package:

Carton box contains 3 blisters of 7 tablets and paper leaflet