Moodapex 50 mg 30 tablets

Tradename

Mudapex

Moodapex

Compound:

Each tablet contains:

Sertraline 50 mg

Properties

Antidepressant. Selective serotonin reuptake inhibitor (5-HT). It has little effect on the reuptake of norepinephrine and dopamine. At therapeutic doses, sertraline blocks the uptake of serotonin by human platelets. Sertraline has no affinity for muscarinic, serotonin, dopamine, adrenergic, histamine, GABA or benzodiazepine receptors. It does not have a stimulating, sedative or anticholinergic effect.

The antidepressant effect is noted by the end of the second week of regular use of sertraline, while the maximum effect is achieved only after 6 weeks.

Unlike tricyclic antidepressants, sertraline does not cause weight gain. Sertraline does not cause mental or physical drug dependence.

Indications

— depression of various etiologies (treatment and prevention);

— obsessive-compulsive disorders (OCD);

panic disorder (with or without agoraphobia);

Dosage and administration

For adults with depression and OCD, the drug is prescribed at an initial dose of 50 mg 1 time / day in the morning or evening. The daily dose can be gradually, not earlier than a week later, increased from 50 mg to a maximum daily dose of 200 mg.

In panic disorders and PTSD, the initial dose is 25 mg 1 time / day in the morning or evening. After a week, you can increase the dose to 50 mg 1 time / day, and then gradually, not earlier than a week later, the daily dose can be increased from 50 mg to a maximum daily dose of 200 mg.

A satisfactory therapeutic result is usually achieved after 7 days from the start of treatment. However, to achieve the full therapeutic effect, regular administration of the drug for 2-4 weeks is required. When treating OCD, it may take 8-12 weeks to achieve a good result. The minimum dose that provides a therapeutic effect is maintained in the future as a maintenance dose.

Contraindications

-pregnancy;

— lactation period;

— hypersensitivity to the components of the drug;

Side effects

On the part of the digestive system: dry mouth, decreased appetite (rarely — increased), up to anorexia, dyspeptic disorders (flatulence, nausea, vomiting, diarrhea), abdominal pain; with prolonged use in 0.8% of cases — an asymptomatic increase in the activity of transaminases in the blood serum (when the drug is discontinued, enzyme activity normalizes).

From the side of the central nervous system and peripheral nervous system: drowsiness, headache, dizziness, tremor, insomnia, anxiety, agitation, hypomania, mania, gait disturbances, weakness.

From the endocrine system: ejaculation disorders, decreased libido, menstrual disorders, hyperprolactinemia, galactorrhea.