Memexa 10 mg, 10 tabs
Trade Name:
Memexa
Composition
Each tablet contains:
Memantine hydrochloride 10 mg
Inactive ingredients:
Avicel, lactose monohydrate, aerosil, talc, magnesium stearate, titanium dioxide, ethanol 96%.
Properties
A remedy for the treatment of dementia. It is a non-competitive antagonist of glutamate NMDA receptors (including in the substantia nigra), as a result, it reduces the excessive stimulating effect of cortical glutamate neurons on the neostriatum, which develops against the background of insufficient release of dopamine. By reducing the flow of Ca2+ into neurons, it reduces the possibility of their destruction.
It has nootropic, cerebral vasodilation, antihypoxic and psychostimulant effects.
Improves impaired memory, increases the ability to concentrate, reduces fatigue and symptoms of depression, reduces spasticity of skeletal muscles caused by diseases or brain damage.
Indications
Moderate to severe dementia in Alzheimer’s disease.
Dosage and administration
The optimal dosing regimen is determined by the doctor. Compliance of the used dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.
When taken orally, the initial dose for adults is 5 mg / day. In the future, the dose can be increased weekly by 5 mg. The average maintenance dose is 10-20 mg / day. The maximum dose is 20 mg / day.
Contraindications
Hypersensitivity to memantine; severe liver failure; pregnancy; lactation period (breastfeeding); children and adolescents under 18 years of age (efficacy and safety of the drug have not been established).
With caution: epilepsy, thyrotoxicosis, predisposition to the development of seizures.
Warnings and precautions:
Side effects
From the immune system: often — hypersensitivity reactions.
On the part of the psyche: often — drowsiness; infrequently — confusion, hallucinations.
From the nervous system: often — dizziness, imbalance; infrequently — gait disturbance; very rarely — convulsions.
Storage
Store at a temperature not exceeding 30°C.
Package:
The carton box contains 1 blister of 10 tabs, paper leaflet.