Brimonidine

Trade Name:

Brimonidine

Composition

Each 1 ml contains:

brimonidine tartrate 0.2%

Other ingredients:

Sodium chloride

Properties

Brimonidine is a selective alpha2-adrenergic agonist that has a stimulating effect on alpha2-adrenergic receptors. When used in the dosage form of eye drops of 0.15%, the maximum decrease in intraocular pressure (IOP) is achieved after 2 hours. The hypotensive effect of brimonidine is provided by reducing the formation and increasing the outflow of intraocular fluid along the uveoscleral pathway.

Indications

— open-angle glaucoma;

— ophthalmic hypertension (in monotherapy or in combination with other drugs that reduce IOP).

Dosage and administration

Locally. In the conjunctival sac of the affected eye, 1 drop 3 times a day with an interval between injections of about 8 hours.

Brimonidine can be used with other ophthalmic drugs to lower IOP. If you use more than 2 drugs, then you need to take a 5-minute break between them.

Contraindications

— hypersensitivity to brimonidine and other components of the drug;

-simultaneous therapy with MAO inhibitors;

— children’s age up to 2 years, low body weight (up to 20 kg);

Side effects

Organ of vision: very often — allergic conjunctivitis, conjunctival hyperemia, itching of the mucous membrane of the eyes and skin of the eyelids; often — a burning sensation, conjunctival folliculosis or follicular conjunctivitis, local allergic reactions from the eyes (including keratoconjunctivitis), blepharitis, blepharoconjunctivitis, visual impairment, cataracts, conjunctival edema.

Central nervous system: often — headache, drowsiness, insomnia, dizziness.

Cardiovascular system: often — increased blood pressure; infrequently — a decrease in blood pressure.

Storage

Store at a temperature not exceeding 30 degrees and use for 30 days after opening.

Package:

The cardboard box contains a 5 ml dropper bottle with dropper, insert leaflet.