
Debacolev
Trade Name:
Debacolev
Composition
Each tablet contains:
levofloxacin hemihydrate 768.67 mg,
which corresponds to the content of levofloxacin 750 mg.
Inactive ingredients:
hypromellose, crospovidone, microcrystalline cellulose, sodium stearyl fumarate.
Properties
A synthetic broad-spectrum antibacterial drug from the group of fluoroquinolones containing levofloxacin, a levorotatory isomer of ofloxacin, as an active substance. Levofloxacin blocks DNA gyrase and topoisomerase IV, disrupts supercoiling and cross-linking of DNA breaks, inhibits DNA synthesis, and causes profound morphological changes in the cytoplasm, cell wall, and membranes of microbial cells.
Levofloxacin is active against most strains of microorganisms, both in vitro and in vivo.
Indications
Treatment of infectious and inflammatory diseases caused by microorganisms sensitive to levofloxacin:
— community-acquired pneumonia;
-complicated urinary tract infections and pyelonephritis;
Dosage and administration
The drug is taken orally at 250 or 500 mg 1 or 2 times / day.Tablets should be swallowed without chewing and with a sufficient amount of liquid (from 0.5 to 1 cup).
The drug can be taken before meals or at any time between meals, because. Food intake does not affect the absorption of the drug.
On average, the course of treatment is 7-14 days, depending on the indications.
Contraindications
-epilepsy;
-myasthenia gravis;
-tendon lesions associated with the use of fluoroquinolones in history;
Side effects
Nervous system: often — headache, dizziness; infrequently — drowsiness, tremor, dysgeusia (taste perversion); rarely — paresthesia, convulsions.
Mental disorders: often — insomnia; infrequently — a feeling of anxiety, confusion.
Digestive system: often — diarrhea, vomiting, nausea; infrequently — abdominal pain, dyspepsia, flatulence, constipation.
Storage
Store at a temperature not exceeding 30°C, in a dry place.
Package:
The carton box contains 2 blisters of 5 tablets, paper leaflet.