
Angiosartan 40 mg
Trade Name:
Angiosartan 40 mg
Composition
Olmesartan medoxomil 40 mg
Properties
Antihypertensive agent, angiotensin II receptor blocker. It has a high selectivity for angiotensin II type 1 receptors (AT1), with the participation of which the main effects of angiotensin II are realized. By blocking these receptors, olmesartan medoxomil prevents and eliminates the vasoconstrictive effect of angiotensin II, causes a secondary increase in plasma renin activity by eliminating negative feedback on renin release and a direct decrease in aldosterone secretion.
In arterial hypertension, olmesartan medoxomil causes a dose-dependent, prolonged decrease in blood pressure.
There is no data on the development of arterial hypotension after taking the first dose of olmesartan medoxomil, tachyphylaxis with prolonged treatment and withdrawal syndrome.
Indications
Essential arterial hypertension.
Mode of application:
— Take orally, daily. The initial dose is 10 mg / day. With insufficient effectiveness, the dose is increased to the optimum — 20 mg / day. If necessary, the dose can be increased to a maximum of 40 mg / day.
Side effects
arterial hypotension, angina pectoris
thrombocytopenia.
vertigo, dizziness, headache, asthenic syndrome (fatigue, drowsiness, general malaise)
Contraindications
Obstruction of the biliary tract, pregnancy, breastfeeding, children and adolescents under 18 years of age, hypersensitivity to olmesartan medoxomil.
Warnings and Precautions:
— the use of olmesartan medoxomil is not recommended in patients with renal insufficiency and patients with impaired liver function.
Storage
Store at a temperature not exceeding 30°C
Package:
Cardboard box contains 4 blisters of 7 tablets