Dexaglobe 2 ml 1 amp

Trade Name:

Dexaglobe suspension for injection

2 ml ampoule

Composition

Each 1 ml contains :

Active ingredients ;

Betamethasone Dipropionate 6,43 mg

(Eq. to 5 mg Betamethasone)

Betamethasone Sodium Phosphate 2,6mg

(Eq. to 2 mg Betamethasone)

Inactive ingredients;

Disodium Phosphate 2 H2O, Monosodium phosphate H2O, Sodium Chloride, Disodium edetate, Polysorbate 80, Benzyl Alcohol, Methyl para-hydroxybenzoate, Propyl para-hydroxybenzoate, Sodium carboxymethyl cellulose, Macrogol 4000, Water for injection

Properties

Dexaglobe sterile aqueous suspension provides a combination of highly soluble and very slightly soluble esters of betamethasone that produce anti inflammatory, anti rheumatic and anti-allergic effects. Prompt therapeutic activity is achieved by the soluble ester betamethasone sodium phosphate , which is quickly absorbed after injection. Sustained activity is provided by betamethasone dipropionate which the only slightly soluble and becomes a repository of slow absorption , thereby controlling symptoms over a prolonged period. The small crystal size of betamethasone dipropionate permits the use of fine gauge needle ( up to 36g ) for intradermal and intralesional administration.

Indications

Dexaglobe is indicated for systemic and local ol treatment of acute and chronic corticosteroid responsive disorders, especially in the following conditions:

Musculoskeletal and soft tissue conditions:

As an adjunctive therapy of short term during the acute attacks or exacerbation

Dosage and administration

Shake well before use.

Dosing requirements are variable and must be individualized on the beets of the specific disease, the severity of the condition and the response of the patient.

The initial dose should be maintained or adjusted until satisfactory reepanes are observed. If a satisfactory clinical response does not occur after a reasonable period of time, treatment with Dexaglobe suspension should be discontinued and an appropriate therapy initiated.

Side effects

Common:

Acne; clumsiness; dizziness; facial flushing; general body discomfort; headache; increased appetite; increased sweating; lightheadedness; nausea; nervousness; pain, swelling, or redness at the injection site; sleeplessness; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Contraindications

-systemic fungal diseases;

-hypersensitivity to betamethasone or other components of the drug;

Warnings and precautions:

Storage

Store at a temperature not exceeding 25°C. Protect from freezing and temperature below 2°C.

Package:

Carton box holds a plastic container with 1 ampoule of 2 ml of suspension.