Somazina 500 mg 4 ml/ 5 amp.

Trade Name:

SOMAZINA 500 mg solution for injection

5 ampoules of 4 ml solution for I/V or I/M injection

Composition

Each 4 ml ampoule contains:

Citicoline 500 mg (as sodium salt)

Inactive ingredients:

Water for injection and hydrochloric acid or sodium hydroxide for pH adjustment.

Properties

Pharmacotherapeutic group: Other psychostimulants and nootropics.

Citicoline stimulates the biosynthesis of structural phospholipids of the neuronal membrane as it is demonstrated in the magnetic resonance spectroscopy studies. Citicoline, through this action, improves the function of the membrane mechanisms, such as the functioning of the ionic exchange pumps and receptors inserted in the latter, the modulation of which is indispensable in neurotransmission.

Citicoline due to its membrane stabilising activity has properties which favour brain oedema reabsorption.

Indications

Stroke, Acute phase and its neurological sequelae.

Traumatic Brain injury and its neurological sequelae.

Cognitive and behavioural impairment secondary to chronic vascular and degenerative cerebral disorders.

Dosage and administration

Adults:

The recommended dose is from 500 to 2,000 mg/ day depending on the severity of the symptoms to be treated.

It can be administered by intramuscular, slow intravenous route( from 3 to 5 minutes depending on the administered dose) or in intravenous drop perfusion ( drippin speed: 40-60 drops per minute ).

Side effects

Very rare:

Psychiatric disorders: hallucinations

Nervous system disorders: cephalea, vertigo;

Contraindications

-allergy to Citicoline or any excipient

-hypertonia of the parasympathetic

Warnings and precautions:

Storage

Store at a temperature not exceeding 30°C

Package:

Carton box holds a plastic container with 5 ampoules each 4 ml solution