Augmentin 62.5mg / ml powder for suspension preparation 20 ml

Trade name:

Augmentin

Composition

Each ml of the finished suspension contains:

Amoxicillin 50 mg

Clavulanic acid 12.5 mg

Properties

Combined preparation of amoxicillin and clavulanic acid — a beta-lactamase inhibitor. Acts bactericidal, inhibits the synthesis of the bacterial wall.

Active against aerobic gram-positive bacteria (including strains producing beta-lactamase): Staphylococcus aureus; aerobic gram-negative bacteria: Enterobacter spp., Escherichia coli, Haemophilus influenzae, Klebsiella spp.,

Moraxella catarrhalis. The following pathogens are sensitive only in vitro: Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus anthracis, Streptococcus pneumoniae, Streptococcus viridans,

Indications

Treatment of infectious and inflammatory diseases caused by sensitive pathogens: 10 respiratory tract infections (bronchitis, pneumonia, pleural empyema, lung abscess);

CRAR

ENT infections (sinusitis, tonsillitis, otitis media); infections of the genitourinary system and pelvic organs (pyelonephritis, pyelitis, cystitis, urethritis, prostatitis, cervicitis, salpingitis, salpingo-oophoritis, tubo-ovarian abscess, endometritis, bacterial vaginitis, septic abortion, postpartum sepsis, pelvioperitonitis, soft chancre); infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatoses, abscess, phlegmon, wound infection); osteomyelitis; postoperative infections. Prevention of infections in surgery.

Contraindications

Hypersensitivity to drug components (including cephalosporins and other betalactam antibiotics); infectious mononucleosis (including when a measles-like rash appears); phenylketonuria; episodes of jaundice or abnormal liver function as a result of amoxicillin / clavulanic acid use in history; C less than 30 ml / min (for tablets 875 mg / 125mg).

Carefully:

Pregnancy, lactation period, severe liver failure, gastrointestinal diseases (including a history of colitis associated with the use of penicillins), chronic renal failure.

Side effects

From the digestive system: nausea, vomiting, diarrhea, gastritis, stomatitis, glossitis, increased activity of hepatic transaminases, in isolated cases — cholestatic jaundice, hepatitis, liver failure (more often in the elderly, men, with prolonged therapy), pseudomembranous and hemorrhagic colitis ( can also develop after therapy), enterocolitis, black «hairy» tongue, darkening of tooth enamel.

From the side of hematopoietic organs: a reversible increase in prothrombin time and bleeding time, thrombocytopenia, thrombocytosis, eosinophilia, leukopenia, agranulocytosis, hemolytic anemia.

From the nervous system: dizziness, headache, hyperactivity, anxiety, change in behavior, seizures.