Sirdalud 4 mg 20 tablets

Tradename

Sirdalud

Composition

Each tablet contains:

tizanidine hydrochloride 4 mg

Auxiliary components:

lactose monohydrate, microcrystalline cellulose, povidone K-30, stearic acid, colloidal hydrophobic silicon dioxide.

Properties

Muscle relaxant of central action. Reduces the increased tone of skeletal muscles, relieves their spasm; reduces muscle resistance during passive movements, increases the strength of voluntary contractions. The muscle relaxant effect of tizanidine is probably due to inhibition of spinal polysynaptic reflexes, which is associated with a decrease in the release of excitatory amino acids from the presynaptic terminals of spinal interneurons, as well as the stimulation of a2-adrenergic receptors.

Tizanidine does not affect the transmission of excitation in neuromuscular synapses.

Indications

Spastic state of skeletal muscles caused by neurological diseases (multiple sclerosis, chronic myelopathy, stroke, degenerative diseases of the spinal cord). Painful spasm of skeletal muscles caused by damage to the spine (cervical and lumbar syndromes) or arising after surgery (for a herniated disc or hip osteoarthritis).

Method of administration and dosage:

The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Contraindications

Hypersensitivity to tizanidine.

Precautions:

Use with caution in patients with impaired liver and kidney function.

Side effects

When using tizanidine in relatively small doses, in rare cases, drowsiness, a feeling of fatigue, dizziness, dry mouth, nausea, a slight decrease in blood pressure are observed; in higher doses — these effects occur more often and are more pronounced, in addition, insomnia, muscle weakness, bradycardia, an increase in serum transaminase activity are possible.

Storage method:

At a temperature not higher than 30 degrees.