Dermovate 0.05% ointment 25 g

Tradename

Dermovate

Dermovate

Compound:

Each gram of ointment contains:

Clobetasol propionate 0.05%

Auxiliary components:

propylene glycol, sorbitan sesquioleate, soft white paraffin.

Properties

Clobetasol is a topical corticosteroid that acts as an anti-inflammatory agent through several mechanisms of inhibition of the late phase of allergic reactions, including a decrease in mast cell density, a decrease in chemotaxis and eosinophil activation, a decrease in cytokine production by lymphocytes, monocytes, mast cells and eosinophils, and suppression of arachidonic acid metabolism. .

Pharmacodynamic effects

GCS for external use have anti-inflammatory, antipruritic and vasoconstrictive properties.

Indications

Clobetasol is a highly active corticosteroid for external use, which is indicated for the short-term treatment of symptoms of inflammation and pruritus in dermatosis sensitive to corticosteroid therapy, and with resistance to less active corticosteroids (for adults, the elderly and children over 1 year old):

— psoriasis (excluding widespread plaque psoriasis);

— dermatosis, difficult to treat;

Dosage and administration

The drug is used externally.

The ointment is recommended for skin lesions accompanied by dryness, hyperkeratosis and thickening of the skin.

Adults, elderly patients and children over 1 year of age

Contraindications

— untreated skin infections;

— rosacea (rosacea);

-acne;

Side effects

Infectious and parasitic diseases: very rarely — opportunistic infections.

From the immune system: very rarely — hypersensitivity, generalized rash.

From the endocrine system: very rarely — depression of the hypothalamic-pituitary-adrenal system, Itsenko-Cushing’s syndrome