Xithrone 500 mg 3 tablets

Trade name:

Xithrone

Xitron

Properties

A broad-spectrum antibacterial drug from the group of azalide macrolides, acts bacteriostatically. By binding to the 50S subunit of ribosomes, it inhibits the peptide translocase at the translation stage, inhibits protein synthesis, slows down the growth and reproduction of bacteria, and in high concentrations has a bactericidal effect. It acts on extra- and intracellularly located pathogens.

Microorganisms may be initially resistant to the action of an antibiotic or may acquire resistance to it.

Indications

Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:

— infections of the upper respiratory tract and ENT organs: pharyngitis, tonsillitis, sinusitis, otitis media;

— infections of the lower respiratory tract: acute bronchitis, exacerbation of chronic bronchitis, pneumonia, incl. caused by atypical pathogens;

Dosage and administration

Azithromycin is taken orally 1 time / day, 500 mg, regardless of food intake.

Adults (including the elderly) and children over 12 years of age weighing over 45 kg:

For infections of the upper and lower respiratory tract, ENT organs, skin and soft tissues: 500 mg 1 time / day for 3 days (course dose — 1.5 g).

Contraindications

— severe hepatic and/or renal insufficiency;

-children under 12 years of age with a body weight of less than 45 kg (for this dosage form);

-breast-feeding;

Side effects

From the digestive system: nausea, vomiting, diarrhea, abdominal pain, loose stools, flatulence, indigestion, anorexia, constipation.

Allergic reactions: itching, skin rashes, angioedema, urticaria.

From the side of the cardiovascular system: palpitations, arrhythmia, ventricular tachycardia, an increase in the QT interval, bidirectional ventricular tachycardia.