Kapron 500 mg 20 tablets

Tradename

Kapron

Composition

Each tablet contains:

Tranexamic acid 500 mg

Auxiliary components:

microcrystalline cellulose, hyprolose, sodium carboxymethyl starch, talc, colloidal silicon dioxide, calcium stearate.

Shell composition: hypromellose, titanium dioxide, talc, macrogol.

Properties

Tranexamic acid is an antifibrinolytic agent that specifically inhibits the activation of profibrinolysin (plasminogen) and its conversion to fibrinolysin (plasmin). It has a local and systemic hemostatic effect in

bleeding associated with increased fibrinolysis, as well as anti-inflammatory, anti-allergic, antiinfectious and antitumor effects by suppressing the formation of kinins and other active peptides involved in allergic and inflammatory reactions. The experiment confirmed the own analgesic activity of tranexamic acid, as well as the supercumulative potentiating effect on the analgesic activity of opiates.

Indications

— bleeding or the risk of bleeding against the background of increased fibrinolysis, as generalized (bleeding during operations and in the postoperative period, postpartum bleeding, manual separation of the placenta, chorionic detachment, bleeding during pregnancy, malignant neoplasms of the pancreas and prostate glands, hemophilia, hemorrhagic complications of fibrinolytic therapy, thrombocytopenic purpura, leukemia, liver disease, previous streptokinase therapy), and local (uterine, cervical conization for carcinoma, nasal, pulmonary, gastrointestinal bleeding, hematuria, bleeding after prostatectomy, to extraction in patients with hemorrhagic diathesis);

-operative interventions on the bladder;

-surgical manipulations for systemic inflammatory reactions (sepsis, peritonitis, pancreatic necrosis, severe and moderate preeclampsia, shock of various etiologies and other critical conditions).

Contraindications

-increased sensitivity to the drug;

— subarachnoid hemorrhage.

With caution: thrombohemorrhagic complications (in combination with heparin and indirect anticoagulants), thrombosis (deep vein thrombophlebitis, thromboembolic syndrome, myocardial infarction), color vision disturbances, hematuria from the upper urinary tract (possible obstruction by a blood clot), renal ).

Side effects

Allergic reactions (rash, pruritus, urticaria), dyspeptic symptoms (anorexia, nausea, vomiting, heartburn, diarrhea), dizziness, weakness, drowsiness, tachycardia, pain in a tight cage, hypotension (with rapid intravenous administration), color vision disturbance, blurred visual perception; thrombosis or thromboembolism (the risk of developing is minimal).

Storage method:

At a temperature not higher than 30 degrees.